This book is a must-have for all health professionals involved in the care of women with high risk pregnancies. It is a concise and practical resource for all perinatal care and a reference for the diagnosis and management of high risk pregnancy.

The fifth edition of this classic, focuses on factors affecting pregnancy, genetics, practical diagnostic techniques, maternal diseases in pregnancy and pregnancy complications, labor, anesthesia, and neonatal considerations.

Dr Queenan is joined in the the fifth edition by a new editor, Katherine Spong, Head of Perinatology at the National Institutes of Health. The book will take an explicitly evidence-based approach this time around and will expand upon several important areas; genetics, doppler ultrasound, prevention, AIDS, group B streptococcus, preeclampsia, and prematurity.

CONTENTS: Part 1: Factors of High-Risk Pregnancy
1 Overview of high-risk pregnancy
2 Maternal nutrition
3 Alcohol and substance abuse
4 Environmental agents and reproductive risk
5 Medications in pregnancy and lactation

Part 2: Genetics
6 Genetic screening for mendelian disorders
7 Screening for neural tube defects
8 First and second trimester screening for fetal aneuploidy

Part 3: Monitoring: Biochemical and Biophysical
9 Fetal endocrinology
10 Fetal lung maturity
11 Antepartum fetal monitoring
12 Interpreting intrapartum fetal heart tracings

Part 4: Maternal Disease
13 Sickle cell disease
14 Thrombocytopenia
15 Inherited and acquired thrombophilias
16 Pathophysiology and diagnosis of thromboembolic disorders in pregnancy
17 Cardiac disease in pregnancy
18 Renal disease in pregnancy
19 Pregnancy in transplant patients
20 Gestational diabetes mellitus
21 Diabetes mellitus
22 Maternal hypothyroidism and hyperthyroidism
23 Asthma
24 Epilepsy
25 Chronic hypertension
26 Systemic lupus erythematosus
27 Perinatal infections
28 Group B streptococcal infections
29 Hepatitis in pregnancy
30 HIV infection

Part 5: Obstetric Complications
31 Genetic and nongenetic causes of spontaneous abortion
32 The incompetent cervix
33 Gestational hypertension - preeclampsia and eclampsia
34 Emergency care in pregnancy
35 Sonographic dating and standard fetal biometry
36 Rh and other blood group alloimmunizations
37 Multiple pregnancy
38 Polyhydramnios and oligohydramnios
39 Prevention of preterm birth
40 Pathogenesis and prediction of preterm delivery
41 Preterm premature rupture of membranes
42 Management of preterm labor
43 Placenta previa and related placental disorders

Part 6: Complications of Labor and Delivery
44 Prolonged pregnancy
45 Cesarean delivery
46 Vaginal birth after cesarean delivery
47 Breech delivery
48 Obstetric analgesia and anesthesia

Part 7: Procedures
49 Genetic amniocentesis and chorionic villus sampling
50 Direct fetal blood sampling: cordocentesis
51 Amnioinfusion: indications and controversies
52 Fetal surgery
53 Problems in the newborn
54 Neonatal encephalopathy and cerebral palsy