This monograph offers a comprehensive review of the wide variety of pathological findings in systemic lupus erythematosus (SLE). Although much information is available on the histological changes in renal lupus, rarely has an attempt been made to depict the lesions of SLE throughout the body. The Armed Forces Institute of Pathology (AFIP), serving as a diagnostic referral center primarily oriented to organ systems, is especially suited to study this systemic disease. The thirteen chapters, compiled by the staff of the AFIP, cover renal, dermal, oral, hematologic, musculoskeletal, pulmonary, cardiovascular, hepatic, ocular, and neural changes as well as the manifestations of lupus in domestic and laboratory animals. The classification of renal lupus is based on the scheme proposed by the World Health Organization. Tables include summaries of autoantibodies present in patients with SLE, drugs implicated in the induction of SLE, correlation of pathological changes with clinical renal signs and symptoms, and a variety of other subjects. With its 185 high-quality photographs (57 in color), this book should be an invaluable resource not only for pathologists, but for clinicians who wish to visualize and understand the lesions of systemic lupus erythematosus. There are 175 pages, 18 tables, 5 color plates, and 365 black-and-white illustrations. The quality of hoth clinical and microscopic illustrations is out-standing. Gynecologists as well as pathologists will find it indispensable.