Introduction.
Acknowledgements.

List of abbreviations.

Part 1 Anatomical and functional organization.

1 The organization of the nervous system.

2 The development of the nervous system.

3 The cells of the nervous system I: Neurones.

4 The cells of the nervous system II: Neuroglial cells.

5 Ion channels.

6 The resting membrane and action potential.

7 The neuromuscular junction and synapses.

8 Nerve conduction and synaptic integration.

9 Neurotransmitters, receptors and their pathways.

10 Skeletal muscle structure.

11 Skeletal muscle contraction.

12 The organization of the spinal cord.

13 Anatomy of the brainstem.

14 Cranial nerves.

15 The organization of the cerebral cortex.

16 The autonomic nervous system.

17 The hypothalamus.

18 Meninges and cerebrospinal fl uid.

19 Blood supply of the central nervous system.

Part 2 Sensory systems.

20 Sensory systems: An overview.

21 Sensory transduction.

22 The somatosensory system.

23 Pain systems I: Nociceptors and nociceptive pathways.

24 Pain systems II: Pharmacology and management.

25 The visual system I: The eye and retina.

26 The visual system II: The visual pathways and subcortical visual areas.

27 The visual system III: Visual cortical areas.

28 The auditory system I: The ear and cochlea.

29 The auditory system II: The auditory pathways and language.

30 The vestibular system.

31 Olfaction and taste.

32 Association cortices: The posterior parietal and prefrontal cortex.

33 Clinical disorders of the sensory pathways.

Part 3 Motor systems.

34 The organization of the motor systems.

35 The muscle spindle and lower motorneurone.

36 Spinal cord motor organization and locomotion.

37 The cortical motor areas.

38 Primary motor cortex.

39 The cerebellum.

40 The basal ganglia: Anatomy and physiology.

41 Basal ganglia diseases and their treatment.

42 Eye movements.

43 Clinical disorders of the motor system.

Part 4 Consciousness and higher brain function.

44 The reticular formation and sleep.

45 Consciousness, theory of mind and general anaesthesia.

46 The limbic system and long-term potentiation.

47 Memory.

48 Emotion, motivation and drug addiction.

49 Neural plasticity and neurotrophic factors I: The peripheral nervous system.

50 Neural plasticity and neurotrophic factors II: The central nervous system.

51 Examination of the nervous system.

52 Investigation of the nervous system.

53 Imaging of the central nervous system.

54 Neurochemical disorders I: Affective disorders.

55 Neurochemical disorders II: Schizophrenia.

56 Neurochemical disorders III: Anxiety.

57 Neurodegenerative disorders.

58 Neurophysiological disorders: Epilepsy.

59 Neuroimmunological disorders.

60 Neurogenetic disorders.

Part 5 Self-assessment case studies.

Case studies and questions.

Answers.

Appendix 1: Major neurotransmitter types.

Appendix 2a: Ascending sensory pathways in the spinal cord.

Appendix 2b: Descending motor tracts.

Appendix 3: Functional and anatomical systems of the cerebellum.

Appendix 4: References.

Index