The 28th edition of the 2009 Report of the American Academy of Pediatrics (AAP) Committee on Infectious Diseases, known to most clinicians as The Red Book, is considered the Bible of pediatric infectious diseases. Updated and exhaustive summary of the clinical manifestations, etiology, epidemiology, diagnostic tests, treatment, isolation and control measures for more than 200 pediatric infectious diseases are included. This reference also includes a number of related topics including management. With more than 350 liaisons and collaborators from the Centers for Disease Control and Prevention, the Food and Drug Administration, the National Insitutes of Health, The Canadian Paediatric Society, the World Health Organization and other, the 12 member Committee issued the current edition reflecting the state of the art at the time of publication. The area of infectious diseases is rapidly emerging and changing. The print book is enhanced with updated information on Red Book Online, a comprehensive pediatric infectious disease website which includes updates, visual references and more.